Fucus extract: cosmetic treatment for under-eye dark circles.
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M Chavan, Y Sun, J Litchauer…
Journal of Cosmetic …, 2014
europepmc.org
Background Dark circles around the eyes are a complex issue with two main possible causes, the accumulation of melanin in the skin around the eyes and the accumulation of heme resulting from blood leakage. The free heme produced in this manner is highly cytotoxic, proinflammatory and pro-oxidative. Aims To evaluate the effect of Fucus extract on heme oxygenase-1 (HO-1) stimulation activity, and to study its in vitro anti-inflammatory, antioxidative, and collagen stimulation activity. Methods The HO-1 stimulation activity was …