Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson's disease models
1. 系统已在2026-07-15 15:28:39对应助文件进行删除
2. 如有需要请重新发布求助信息
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
S Du, Q Long, Y Zhou, J Fu, H Wu, L Yang, Y Xie…
Cell, 2026
cell.com
Mitochondrial transplantation holds significant potential for the treatment of mitochondrial diseases. However, how to efficiently deliver exogenous mitochondria to somatic cells or tissues remains unresolved. We present a mitochondrial transplantation approach to deliver mitochondria into the cells and tissues of mice and monkeys with high efficiency, based on encapsulating mitochondria with vesicles derived from the plasma membrane of erythrocytes. Treatment with encapsulated mitochondria complemented the loss, deletion, or …
